Dopamine beta Hydroxylase (DBH) Sheep Polyclonal Antibody

CAT#: TA309110

Sheep Anti-Dopamine β-Hydroxylase, N-Terminus, Human Antibody

Product Images

Western blot of human adrenal medulla lysate showing specific immunolabeling of the ~75k DBH protein.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Primate
• Host: Sheep
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
• Formulation: 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 75 kDa
• Gene Name: dopamine beta-hydroxylase
• Database Link:
  NP_000778
  Entrez Gene 1621 Human
  UniProt ID P09172
• Background: The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. [provided by RefSeq]
• Synonyms: DBM

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Metabolic pathways, Tyrosine metabolism