DOPA Decarboxylase (DDC) Rabbit Polyclonal Antibody
Rabbit Anti-DOPA Decarboxylase, Human Antibody
Product Datasheet for 'TA309108'
|Recommend Dilution||WB: 1:1000|
|Reactivity||bovine, dog, guinea porcine, human, rabbit, rat, sheep|
|Immunogen||Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH|
|Formulation||100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.|
|Predicted Protein Size||55 kDa|
|Gene Name||dopa decarboxylase|
|Background||The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]|
|Protein Families||Druggable Genome|
|Protein Pathways||Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Tryptophan metabolism, Tyrosine metabolism|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.