Lamin B1 (LMNB1) Rabbit Polyclonal Antibody

CAT#: TA308921

Rabbit polyclonal antibody to Lamin B1 (lamin B1)

Product Images

Sample (30 ug of whole cell lysate). A: NIH-3T3. 7.5% SDS PAGE. TA308921 diluted at 1:5000.

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  Sample (30 ug whole cell lysate). A:A431. B:H1299. C:HeLa S3. 7.5% SDS PAGE. TA308921 diluted at 1:5000

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  Immunohistochemical analysis of paraffin-embedded Colon ca, using Lamin B1 antibody (TA308921) antibody at 1:250 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:1000-1:10000
• Reactivities: Human (Predicted: Bovine, Rhesus Monkey)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 289 and 574 of Lamin B1 (Uniprot ID#P20700)
• Formulation: 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 66 kDa
• Gene Name: lamin B1
• Database Link:
  NP_005564
  Entrez Gene 4001 Human
  UniProt ID P20700
• Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. [provided by RefSeq]
• Synonyms: ADLD; LMN; LMN2; LMNB
• Note: Seq homology of immunogen across species: Rhesus Monkey (100%), Bovine (100%)