FTCD Rabbit Polyclonal Antibody

CAT#: TA308819

Rabbit Polyclonal antibody to FTCD (formiminotransferase cyclodeaminase)

Product Images

Sample (50 ug of whole cell lysate). A: mouse liver. 7.5% SDS PAGE. TA308819 diluted at 1:1000.

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  Sample (30 ug of whole cell lysate). A: Hep G2. 7.5% SDS PAGE. TA308819 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded NCIN87 xenograft, using FTCD (TA308819) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse (Predicted: Pig, Rat, Bovine)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 251 of FTCD (Uniprot ID#O95954)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 59 kDa
• Gene Name: formimidoyltransferase cyclodeaminase
• Database Link:
  NP_996848
  Entrez Gene 14317 MouseEntrez Gene 89833 RatEntrez Gene 10841 Human
  UniProt ID O95954
• Background: FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. [supplied by OMIM]
• Synonyms: LCHC1
• Note: Seq homology of immunogen across species: Pig (84%), Rat (89%), Bovine (88%)

Reference Data

• Protein Pathways: Histidine metabolism, Metabolic pathways, One carbon pool by folate