GBA Rabbit Polyclonal Antibody

CAT#: TA308240

Rabbit Polyclonal antibody to GBA (glucosidase, beta, acid)

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 Product Datasheet for 'TA308240'

USD 416.00

In Stock

    • 100 ul

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Product Data
Applications WB, IHC, IF
Recommend Dilution ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity Human (Predicted: Chimpanzee)
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 352 and 536 of GBA (Uniprot ID#P04062)
Isotype IgG
Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Predicted Protein Size 60kDa
Gene Name glucosylceramidase beta
Background This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]
Synonyms GBA1|GCB|GLUC
Note Seq homology of immunogen across species: Chimpanzee (100%)
Reference Data
Protein Families Druggable Genome
Protein Pathways Other glycan degradation, Sphingolipid metabolism, Metabolic pathways, Lysosome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.