GLE1 Rabbit Polyclonal Antibody

CAT#: TA307943

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Rabbit polyclonal antibody to GLE1 (GLE1 RNA export mediator homolog (yeast))


 Product Datasheet for 'TA307943'

USD 415.00


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In Stock

Size
    • 100 ul


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Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant protein fragment contain a sequence corresponding to a region within amino acids 414 and 646 of GLE1
Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Predicted Protein Size 75 kDa
Gene Name GLE1, RNA export mediator
Background This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms GLE1L; hGLE1; LCCS; LCCS1
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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