VEGFA Rabbit Monoclonal Antibody [Clone ID: EP1176Y]

CAT#: TA303731

Rabbit monoclonal antibody against VEGF (C-term)(EP1176Y)

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 Product Datasheet for 'TA303731'

USD 534.00

In Stock

    • 100 ul

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Product Data
Clone Name EP1176Y
Applications IHC, IF, FC
Recommend Dilution IP: 1:50; FC: 1:100; IHC-P: Use at an assay dependent dilution; ICC/IF: 1:250 - 1:500
Reactivity Mouse, Human
Host Rabbit
Clonality Monoclonal
Immunogen A synthetic peptide corresponding to residues on the C-terminus of human VEGF was used as an immunogen.
Isotype IgG
Formulation PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Predicted Protein Size 27 kDa
Gene Name vascular endothelial growth factor A
Background This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq].
Reference Data
Protein Families Secreted Protein, Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, mTOR signaling pathway, VEGF signaling pathway, Focal adhesion, Pathways in cancer, Renal cell carcinoma, Pancreatic cancer, Bladder cancer
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.