Vasopressin V1b receptor(AVPR1B) Goat Polyclonal Antibody
Goat Polyclonal Antibody against AVPR1B
Product Datasheet for 'TA303370'
|Recommend Dilution||ELISA: 1:32,000. WB: 0.05-0.2µg/ml.|
|Reactivity||Test: Human. Expected from seq similarity: Human|
|Immunogen||Peptide with sequence C-PRDLELADGEGTAE, from the C-Terminus of the protein sequence according to NP_000698.1.|
|Formulation||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purification||Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Gene Name||arginine vasopressin receptor 1B|
|Background||The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq].|
|Protein Families||GPCR, Transmembrane, Druggable Genome|
|Protein Pathways||Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.