BMPR1A Goat Polyclonal Antibody

CAT#: TA303097

Goat Polyclonal Antibody against BMPR1A

Antibody Service


 Product Datasheet for 'TA303097'

USD 360


Availability*
In Stock

Size
    • 100 ug

Product images

Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1:16,000. WB: 1-3µg/ml.
Reactivity Test: Human. Expected from seq similarity: Human, Dog
Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence C-KSDSDQKKSEN, from the internal region of the protein sequence according to NP_004320.2.
Isotype Goat IgG
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Gene Name bone morphogenetic protein receptor type 1A
Background The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq].
Synonyms 10q23del|ACVRLK3|ALK3|CD292|SKR5
Reference Data
Protein Families Protein Kinase, ES Cell Differentiation/IPS, Transmembrane, Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.