DAZL Goat Polyclonal Antibody

CAT#: TA303047

Goat Polyclonal Antibody against DAZL

Product Images

TA303047 (1ug/ml) staining of Rat Testes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  TA303047 staining of paraffin embedded Mouse Testis. This data was obtained using a previous batch.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:64,000. WB: 0.1-0.3µg/ml.
• Reactivities: Human, Mouse (Expected from sequence similarity: Rat, Dog, Cow)
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-GNGPQKKSVDR, from the internal region of the protein sequence according to NP_001342.2.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: deleted in azoospermia like
• Database Link:
  NP_001342
  Entrez Gene 13164 MouseEntrez Gene 680486 RatEntrez Gene 477055 DogEntrez Gene 1618 Human
  UniProt ID Q92904
• Background: The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. [provided by RefSeq]
• Synonyms: DAZH; DAZL1; DAZLA; SPGYLA