SRP1 (KPNA1) Goat Polyclonal Antibody

CAT#: TA302916

Goat Polyclonal Antibody against KPNA1

Product Images

TA302916 staining (1ug/ml) of HeLa lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:32,000. WB: 1-3µg/ml.
• Reactivities: Human (Expected from sequence similarity: Mouse, Rat, Dog, Pig, Cow)
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence TTPGKENFRLKSY-C, from the N Terminus of the protein sequence according to NP_002255.1.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: karyopherin subunit alpha 1
• Database Link:
  NP_002255
  Entrez Gene 16646 MouseEntrez Gene 288064 RatEntrez Gene 478585 DogEntrez Gene 3836 Human
  UniProt ID P52294
• Background: Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V(D)J recombination. Two transcript variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq]
• Synonyms: IPOA5; NPI-1; RCH2; SRP1