p27 KIP 1(CDKN1B) Goat Polyclonal Antibody

CAT#: TA302712

Goat Polyclonal Antibody against CDKN1B

Antibody Service


 Product Datasheet for 'TA302712'

USD 360


Availability*
2 Weeks

Size
    • 100 ug

Product images

Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1:32,000. WB: 1-3µg/ml.
Reactivity Test: Human. Expected from seq similarity: Human, Mouse, Rat, Cow, Dog
Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence C-EQTPKKPGLRRRQT, from the C Terminus of the protein sequence according to NP_004055.1.
Isotype Goat IgG
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration 0.5 mg/ml
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Gene Name cyclin-dependent kinase inhibitor 1B
Background This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].
Synonyms CDKN4|KIP1|MEN1B|MEN4|P27KIP1
Reference Data
Protein Families Druggable Genome
Protein Pathways ErbB signaling pathway, Cell cycle, Pathways in cancer, Prostate cancer, Chronic myeloid leukemia, Small cell lung cancer
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.