Apolipoprotein E(APOE) Goat Polyclonal Antibody

CAT#: TA302644

Goat Polyclonal Antibody against APOE

Antibody Service


 Product Datasheet for 'TA302644'

USD 360


Availability*
In Stock

Size
    • 100 ug

Product images

Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1:2,000. WB: 0.1-0.3µg/ml.
Reactivity Test: Human. Expected from seq similarity: Human
Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence C-VGTSAAPVPSDNH, from the C Terminus of the protein sequence according to NP_000032.1.
Isotype Goat IgG
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration 0.5 mg/ml
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Predicted Protein Size 34.2 kDa
Gene Name apolipoprotein E
Background Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq].
Synonyms AD2|APO-E|LDLCQ5|LPG
Reference Data
Protein Families Secreted Protein, Stem cell - Pluripotency, Adult stem cells, Druggable Genome
Protein Pathways Alzheimer's disease
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.