Nucleophosmin(NPM1) Rabbit Polyclonal Antibody

CAT#: TA301725

Rabbit Polyclonal Antibody against Nucleophosmin, mutant - AML Marker

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 Product Datasheet for 'TA301725'

USD 416.00


Availability*
In Stock

Size
    • 100 ul

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Specifications

Product Data
Applications WB, IF
Recommend Dilution WB: 1: 1000, IHC: 1:50-1: 100, FC: 1: 100
Reactivity human
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide made to a C-terminal region of human mutant nucleophosmin (exact sequence is within residues 250-298).
Isotype IgG
Formulation 100 mM glycine, 65 mM Tris, pH 7.0 in 50% glycerol
Reconstitution Method Reconstitute with PBS (pH7.3). To use this carrier-free antibody for conjugation experiment, we strongly recommend you to perform another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Affinity purified
Gene Name nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Background Nucleophosmin (NPM) is a multi-functional protein that is involved in many cellular activities including cell growth, proliferation and transformation. It is frequently overexpressed in solid tumors, and has recently been found to be mutated and aberrantly localized in the cytoplasm of leukaemic blasts in patients with acute myeloid leukemia (AML).
Synonyms B23|NPM
Reference Data
Protein Families Stem cell - Pluripotency, Transcription Factors, Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.