S100A12 Rabbit Polyclonal Antibody

CAT#: TA301490

Rabbit Polyclonal Antibody against S100A12


USD 457.00

5 Days*

Size
    • 100 ul

Product Images

Frequently bought together (3)
Transient overexpression lysate of S100 calcium binding protein A12 (S100A12)
    • 100 ug

USD 436.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 200.00


Recombinant protein of human S100 calcium binding protein A12 (S100A12), 20 µg
    • 20 ug

USD 867.00

Other products for "S100A12"

Specifications

Product Data
Applications ICC/IF, WB
Recommended Dilution Immunocytochemistry/ Immunofluorescence: 1:500, Western Blot: 1:1000
Reactivities Human (Does not react with: Mouse, Rat)
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Full length human S100A12 protein [Swiss-Prot# P80511] expressed in E. coli.
Formulation 0.1% sodium azide
Purification Whole antisera
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name S100 calcium binding protein A12
Background S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE. S100A12 has also been shown to have anti-microbial properties.
Synonyms CAAF1; CAGC; CGRP; ENRAGE; MRP-6; MRP6; p6
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.