c-Myb(MYB) Rabbit Monoclonal Antibody [Clone ID: EP769Y]

CAT#: TA300706

Rabbit Monoclonal Anti-v-Myb + c-Myb (phospho S11) Antibody [EP769Y] - ChIP Grade

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 Product Datasheet for 'TA300706'

USD 519


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Size
    • 100 ul

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Specifications

Product Data
Clone Name EP769Y
Applications WB, IHC
Recommend Dilution WB: 1:1000 - 1:5000; IHC-P: Use at an assay dependent dilution; ICC/IF: 1:100 - 1:250; IP: 1:50; ChIP: Use at an assay dependent dilution
Reactivity Human (Does not react with: Mouse, Rat)
Host Rabbit
Clonality Monoclonal
Immunogen A synthetic peptide corresponding to residues near the N-terminus of human c-myb was used as an immunogen.
Isotype IgG
Formulation PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Gene Name MYB proto-oncogene, transcription factor
Background The c-Myb proto-oncogene is a 75 kDa protein involved in growth regulation and differentiation in many different cell types but it is predominantly expressed in immature hemopoietic cells where it plays an important role in cell proliferation. c-Myb activity is directly regulated by cyclin D1 and CDKs and it is believed that c-Myb activity is regulated during the cell cycle in hematopoietic cells (2). Disrupting c-myb function might, therefore, prove an effective therapeutic strategy for controlling leukemic cell growth (3). c-Myb binds to promoter sequences of genes such as c-Myc or Bcl-2 that are expressed in cutaneous T-cell lymphoma.
Synonyms Cmyb|c-myb|c-myb_CDS|efg
Note Is unsuitable for Flow Cyt.
Reference Data
Protein Families ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transcription Factors, Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.