SARS-CoV-2 Spike Protein Rabbit Polyclonal Antibody

SKU TA160070

Rabbit Polyclonal Anti-SARS-CoV-2 Spike Protein Antibody

Product Data

• Application: ELISA, WB
• Recommended Dilution: ELISA: 1 ug/ml; WB: 1 ug/ml
• Reactivity: SARS-CoV, SARS-CoV-2
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antibody was raised against a peptide corresponding to 20 amino acids within the last 50 amino acids of SARS-CoV-2 Spike glycoprotein.; Predicted reactivity based on immunogen sequence: SARS-CoV Spike proteins: 100%
• Buffer: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: S Protein
• Database Link:
  QHD43416
  P0DTC2
• Background: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection. The spike protein is the major target for neutralizing antibodies and vaccine development. The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19.

Reference Data