CD8A Mouse Monoclonal Antibody [Clone ID: MIL-12]
Specifications
| Product Data | |
| Clone Name | MIL-12 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: Use 10 µl of Neat antibody to label 10e6 cells in 100 µl. |
| Reactivity | Porcine |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Porcine mesenteric lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells of the P3-X63-Ag.653 myeloma cell line. |
| Specificity | This antibody recognises a subset of T cells. |
| Buffer | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: PE State: Lyophilzed purified IgG fraction. Label: R. Phycoerythrin (RPE) |
| Reconstitution Method | Restore with 1.0 ml distilled water. |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | PE |
| Storage | Store the antibody undiluted Prior to and After reconstitutionat 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Database Link | |
| Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. |
| Synonyms | CD8 alpha chain, CD8A, MAL |
| Reference Data | |
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