CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: MEM-154]
$440.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | MEM-154 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: Analysis of Human blood cells using 20 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human granulocytes |
| Specificity | This antibody reacts with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). CD16 is a low affinity receptor for aggregated IgG (FcgRIII antigen). The antibody reacts with CD16+ granulocytes. |
| Buffer | Phosphate buffered saline (PBS) containing 15 mM Sodium Azide as presrevative Label: PE State: Liquid purified IgG fraction Label: Conjugated with R-Phycoerythrin under optimum conditions |
| Purification | Size-Exclusion Chromatography. |
| Conjugation | PE |
| Storage | Store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | Fc fragment of IgG receptor IIIa |
| Database Link | |
| Background | CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype. |
| Synonyms | FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2 |
| Reference Data | |
| Protein Categories | ADC Targets, Allergies and autoimmune diseases, CD Markers, Membrane Proteins, Secreated Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.