TNF Mouse Monoclonal Antibody [Clone ID: CC327]
Specifications
| Product Data | |
| Clone Name | CC327 |
|---|---|
| Application | ELISA, FC |
| Recommended Dilution | Flow Cytometry: Membrane permeabilisation is required for this application. ELISA: This reagent may be used as a Capture antibody in ELISA assays for bovine TNF alpha in combination with SM2228B as Detection reagent. |
| Reactivity | Bovine |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Recombinant bovine TNF alpha. |
| Specificity | This antibody clone CC327 recognizes Bovine TNF alpha. |
| Buffer | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction from tissue culture supernatant |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G. |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Database Link | |
| Background | Tumor Necrosis Factor alpha (TNF alpha) is a 17.5kDa cytokine, expressed by many different stimulated cell types including monocytes, macrophages, endothelial cells, fibroblasts and both T and B-lymphocytes. The production of TNF alpha is induced by a variety of factors, dependant upon cell type and includes bacterial toxins, IL-1, PDGF, IFN-beta, NGF, Oncostatin M and viral infections. The presence of TNF alpha is responsible for diverse immunomodulatory, anti-tumour and toxic effects and under certain conditions is also capable of self-stimulation and inhibition. |
| Synonyms | TNF, TNF-a, TNFA, TNFSF2, Cachectin |
| Reference Data | |
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