HLA Class II DR Rat Monoclonal Antibody [Clone ID: YD1/63.4.10]

CAT#: SM2201P

HLA Class II DR rat monoclonal antibody, clone YD1/63.4.10, Purified

Specifications

Product Data

• Clone Name: YD1/63.4.10
• Applications: FC, IHC
• Recommended Dilution: Flow Cytometry: Use 10 µl of 1/50-1/200 diluted antibody to label 10e6 cells or 100 µl Human whole blood.
  This product is routinely tested in Flow Cytometry on Human peripheral blood lymphocytes.
  Immunohistochemistry on Frozen Sections.
  Recommended Positive Control: Tonsil.
  This Clone is reported to work in Parafin-Embedded Sections.
• Reactivities: Human
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: DAUDI cells.
• Specificity: This antibody recognizes a monomorphic determinant of Human HLA DR which is an MHC class II cell surface receptor expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages and activated T lymphocytes.
• Formulation: PBS containing 0.09% Sodium Azide as preservative
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Background: The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class II proteins encoded by the HLA which are HLA DP, HLA DQ and HLA DR.
• Synonyms: HLA-DR, HLA class II histocompatibility antigen DR, MHC class II antigen DR