ICAM2 Rat Monoclonal Antibody [Clone ID: mIC2/4 (3C4)]

CAT#: SM2101LE

ICAM2 rat monoclonal antibody, clone mIC2/4 (3C4), Low Endotoxin

Product Images

Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD102: LOW ENDOTOXIN.

Specifications

Product Data

• Clone Name: mIC2/4 (3C4)
• Applications: FC, FN, IP
• Recommended Dilution: Flow Cytometry: 1/50 - 1/200; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
  Immunoprecipitation.
  Functional Assays.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: COS cells transfected with murine ICAM-2. Spleen cells from immunised Lewis rats were fused with cells of the Mouse P3X63Ag8.653 myeloma cell line.
• Specificity: This antibody recognises intercellular adhesion molecule-2 (ICAM-2), also known as CD102. Clone mIC2/4 is reported to inhibit interactions between CD102 and LFA-1.
• Formulation: PBS, pH7.4
  State: Low Endotoxin
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: Affinity chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: intercellular adhesion molecule 2
• Database Link:
  UniProt ID P13598
• Background: Murine CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is constitutively expressed on endothelial cells. CD102 interacts with the CD11a/CD18 integrin LFA-1. Reports suggest that CD102 may play a role in lymphocyte re-circulation and T-cell activation.
• Synonyms: ICAM-2
• Note: Endotoxin Level: less than 0.01 EU/µg