LAIR1 Mouse Monoclonal Antibody [Clone ID: NKTA255]

CAT#: SM2048PS

LAIR1 mouse monoclonal antibody, clone NKTA255, Aff - Purified

Product Images

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD305.

Specifications

Product Data

• Clone Name: NKTA255
• Applications: FC, IP, WB
• Recommended Dilution: Flow Cytometry: 1/50 - 1/100; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
  Immunoprecipitation.
  Western Blot: this antibody detects a band of approximately 40 kDa.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: NK cells lines B12.100 and AM.25. Spleen cells from immunised mice were fused with cells of the P3U1 myeloma cell line.
• Specificity: This antibody recognises leukocyte-associated Ig-like receptor-1 (LAIR-1). Clone NKTA255 is reported to inhibit NK cell triggering via CD16 molecules. We recommend the use of SM2048A for this purpose.
• Formulation: PBS, pH7.4 containing 0.09% Sodium Azide
  State: Aff - Purified
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: Affinity chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: leukocyte associated immunoglobulin like receptor 1
• Database Link:
  Entrez Gene 3903 Human
  UniProt ID Q6GTX8
• Background: LAIR-1 is a 40kD cell surface molecule that functions as an inhibitory receptor on natural killer cells, monocytes and T cells. LAIR-1, otherwise known as CD305, is also expressed by other haematopoeitic cells including B cells, but is not expressed by nonhaematopoietic, platelets or erythrocytes.
• Synonyms: LAIR-1, hLAIR1