IGF2R Mouse Monoclonal Antibody [Clone ID: MEM-238]

CAT#: SM2004P

IGF2R mouse monoclonal antibody, clone MEM-238, Purified

Product Images

Western Blotting analysis (non-reducing conditions) of CD222 in whole cell lysate of JURKAT human peripheral blood T cell leukemia cell line. Lane 1: immunostaining with anti-CD222 (MEM-238). Lane 2: immunostaining with Isotype mouse IgG1 control (AM03095PU-N)

Specifications

Product Data

• Clone Name: MEM-238
• Applications: FC
• Recommended Dilution: Flow cytometry: 1/25 - 1/50; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody recognises CD222. Clone MEM-238 recognises an epitope located in the region between extracellular domains 2 and 5 (aa 192-697) of CD222. CD222 is primarily expressed intracellularly with a small percentage of molecules being located at the cell surface (5 - 10%).
• Formulation: PBS containing 0.09% Sodium Azide
  State: Purified
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: Affinity chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: insulin like growth factor 2 receptor
• Database Link:
  Entrez Gene 3482 Human
  UniProt ID P11717
• Background: CD222 is a 250 KD transmembrane protein originally identified as the IGF II receptor. CD222 is ubiquitously expressed and is involved with internalization of a variety of ligands.
• Synonyms: CI-MPR, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, M6P/IGF2 receptor, CI Man-6-P receptor, M6PR, Late Endosome Marker, M6P/IGF2R, MPR 300