Granzyme B (GZMB) Mouse Monoclonal Antibody [Clone ID: GB11]
$470.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | GB11 |
|---|---|
| Application | ELISA, FC, IF, IHC, IP |
| Recommended Dilution | ELISA: 2-5 µg/ml. Immunoprecipitation. Immunofluorescence. Immunohistochemistry on Frozen Sections. Flow Cytometry: Use 10 µl of 1/10-1/100 diluted antibody to label 106 cells or 100 µl whole blood (Membrane permeabilisation is required). |
| Reactivity | Chimpanzee, Human, Monkey |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified human Granzyme B. |
| Specificity | This antibody recognises the serine protease Granzyme B. This antibody has been reported to function as a Capture reagent in ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (SM1805B) as detection reagent. |
| Buffer | Tris buffered saline containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction |
| Concentration | lot specific |
| Purification | Affinity chromatography on Protein A |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | granzyme B |
| Database Link | |
| Background | Ganzyme B is important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death. |
| Synonyms | Granzyme-2, CGL1, CTSGL1, CSPB, CTLA1, CTLA-1, GRB, SECT, Fragmentin-2 |
| Reference Data | |
| Protein Categories | ADC Targets, Cytokines, Enzyme: Peptidases, Intracellular Proteins, Secreated Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.