Integrin alpha E (ITGAE) Mouse Monoclonal Antibody [Clone ID: LF61]
$565.00
5 Days*
Specifications
| Product Data | |
| Clone Name | LF61 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: Use 5 µl of neat-1/10 diluted antibody to label 106 cells in 100 µl. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Hairy cell leukaemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSO myeloma cell line. |
| Specificity | This antibody recognizes the Human CD103 cell surface antigen. Other species not tested. |
| Buffer | PBS Label: FITC State: Liquid purified IgG faction Stabilizer: 1% BSA Preservative: 0.09% Sodium Azide Label: Fluorescein Isothiocyanate Isomer 1 Absorption emission: 490 nm / 525 nm |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein A |
| Conjugation | FITC |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | integrin subunit alpha E |
| Database Link | |
| Background | CD103/Integrin alpha E is a new member of the integrin series of adhesion molecules containing the beta7 subunit. This antigen defines a developmentally important subset of T cells, namely mucosal T cells including all IEL (intraepithelial lymphocytes) and ~20% of lamina propria T cells. Expression of CD103 is more restricted outside these mucosal organs, appearing at lower levels on T cell subsets of the lymph node, dendritic epidermis and periphery. In non-epithelial CD103+ T cells there is a bias toward expression on CD8+ cells. Integrin alpha E is a heterodimer comprising a 150kDa alpha chain and a 120kDa beta chain. Integrin alpha E is expressed by approximately 1% of peripheral blood lymphocytes, activated T lymphocytes and by hairy cell leukaemia cells. The antigen is also expressed by intraepithelial lymphocytes. It has recently been shown to be identical to the alpha E integrin. |
| Synonyms | Integrin alpha-E, Integrin alpha-IEL, HML-1 antigen, ITGAE |
| Reference Data | |
| Protein Categories | CD Markers, Intracellular Proteins, Membrane Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.