TLR4 Mouse Monoclonal Antibody [Clone ID: HTA125]

CAT#: SM1677LE

Reviews ()
Write a review

TLR4 mouse monoclonal antibody, clone HTA125, Low Endotoxin



USD 831.00


Availability*
5 Days

Size
    • 500 ug


Product images

Specifications

Product Data
Clone Name HTA125
Applications FC, FN, IP, WB
Recommended Dilution Flow Cytometry: Use 10 μl of 1/10-1/25 diluted antibody to label 106 cells or 100 μl whole blood.
Immunoprecipitation.
Western Blot.
Functional Assays.
Reactivity Canine, Guinea Pig, Human, Monkey, Porcine
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Ba/F3 cell line expressing TLR4 (CD284).
Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Specificity This antibody recognises the Toll like receptor 4 (TLR4) cell surface antigen.
This antibody has been demonstrated to block activation of monocytes with LPS.
Formulation PBS
State: Low Endotoxin
State: Liquid purified IgG fraction
Stabilizer: None
Preservative: None
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.
Synonyms Toll-like receptor 4
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway
Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Antibody Performance Guarantee banner
ANTIBODY VALIDATION 101
Clone ID reveals the Source of Monoclonal Antibodies