TLR4 Mouse Monoclonal Antibody [Clone ID: HTA125]

CAT#: SM1677LE

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TLR4 mouse monoclonal antibody, clone HTA125, Low Endotoxin

USD 831.00

5 Days

    • 500 ug

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Product Data
Clone Name HTA125
Applications FC, FN, IP, WB
Recommended Dilution Flow Cytometry: Use 10 μl of 1/10-1/25 diluted antibody to label 106 cells or 100 μl whole blood.
Western Blot.
Functional Assays.
Reactivity Canine, Guinea Pig, Human, Monkey, Porcine
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Ba/F3 cell line expressing TLR4 (CD284).
Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Specificity This antibody recognises the Toll like receptor 4 (TLR4) cell surface antigen.
This antibody has been demonstrated to block activation of monocytes with LPS.
Formulation PBS
State: Low Endotoxin
State: Liquid purified IgG fraction
Stabilizer: None
Preservative: None
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.
Synonyms Toll-like receptor 4
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway
Customer Reviews 
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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