Factor I (CFI) Mouse Monoclonal Antibody [Clone ID: OX-21]
$435.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | OX-21 |
|---|---|
| Application | ELISA, FC, IP, R, WB |
| Recommended Dilution | ELISA: 1/40000 (Plates were coated with 2 ug/ml purified Factor I, and HRPO-Streptavidin was used for detection). Western Blot. Flow Cytometry. Immunoprecipitation. Radioimmunoassay. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human complement Factor I. Donor: Immunized FI cross DBA/2 x BALB/c mouse spleen cells Fusion Partner: NS-1 mouse myeloma |
| Specificity | Anti-human factor I (C3b inactivator) monoclonal antibody clone OX-21 recognizes human complement protein factor I. Factor I has two polypeptide chains, 56kD and 38kD. This antibody detects only the 56kD chain. This clone has been reported not to cross react with Rat. |
| Buffer | PBS Label: Biotin State: Liquid purified IgG fraction Stabilizer: EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml Preservative: 0.02% Sodium Azide |
| Concentration | lot specific |
| Conjugation | Biotin |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | complement factor I |
| Database Link | |
| Background | Factor I is a serine protease with a high degree of specificity for C3b and C4b. It requires protein cofactors for cleavage of these complement protein breakdown products: Factor H, CR1 and MCP are required for C3b cleavage and C4bp or CR1 for C4b cleavage. |
| Synonyms | CFI, IF, KAF, AHUS3, C3BINA, C3b-INA |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Enzyme: Peptidases, Immune system diseases, Nervous system Diseases, Secreated Proteins |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.