Cytokeratin 18 (KRT18) Mouse Monoclonal Antibody [Clone ID: DC-10]

CAT#: SM1360F

Cytokeratin 18 (KRT18) mouse monoclonal antibody, clone DC-10, FITC

Product Images

Immunohistochemistry staining of human colon (paraffin sections) using anti-cytokeratin 18 (clone DC-10).

Specifications

Product Data

• Clone Name: DC-10
• Applications: FC, IF, IHC
• Recommended Dilution: Flow Cytometry Analysis and Immunofluorescence (5-10 µg/ml).
  This Monoclonal antibody is reported to work in Immunohistochemistry on Paraffin Sections (1/50).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human breast carcinoma cell line PMC-42.
• Specificity: The antibody DC-10 reacts with Cytokeratin 18 (45 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
  Negative Species: Porcine, Mouse, Rat, Hamster, Bovine, Sheep and Canine (Dog).
• Formulation: PBS
  Label: FITC
  State: Liquid purified Ig fraction
  Stabilizer: 0.2% (w/v) high-grade BSA (Protease free)
  Preservative: 15 mM Sodium Azide
  Label: Fluorescein isothiocyanate under optimum conditions. Reagent is free of unconjugated
• Concentration: lot specific
• Purification: Protein A Chromatography
• Conjugation: FITC
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: keratin 18
• Database Link:
  Entrez Gene 3875 Human
  UniProt ID P05783
• Background: Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families. Cytokeratin 18 belongs to type I family (acidic cytokeratins).
• Synonyms: Cytokeratin-18, CK18, Keratin-18, Keratin 18, KRT18, CYK18, K18