CD105 (ENG) Mouse Monoclonal Antibody [Clone ID: SN6]
Specifications
| Product Data | |
| Clone Name | SN6 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl. |
| Reactivity | Equine, Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Partially purified cell membrane antigens from fresh leukaemia cells |
| Specificity | This antibody recognises the human CD105 cell surface antigen, a glycoprotein homodimer of 95 kD subunits. |
| Buffer | PBS, pH 7.4, containing 0.09% sodium azide as preservative and 1% BSA as stabilizer. Label: PE State: Lyophilized purified IgG fraction. Label: R. Phycoerythrin (RPE) |
| Reconstitution Method | Restore with 1.0 ml distilled water. |
| Purification | Affinity Chromatography on Protein G. |
| Conjugation | PE |
| Storage | Prior to and following reconstitution store the antibody undiluted at 2-8°C. DO NOT FREEZE! This Product is photosensitive and should be protected from light. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | endoglin |
| Database Link | |
| Background | CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2. |
| Synonyms | ENG, END, HHT1, ORW, ORW1 |
| Reference Data | |
| Protein Categories | CD Markers, Growth Factors, Membrane Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.