CD51 (ITGAV) Mouse Monoclonal Antibody [Clone ID: 23C6]

CAT#: SM1135P

CD51 (ITGAV) mouse monoclonal antibody, clone 23C6, Purified

Specifications

Product Data

• Clone Name: 23C6
• Applications: FC, IP
• Recommended Dilution: Flow Cytometry: Use 10 µl of 1/40-1/80 diluted antibody to label 10e6 cells in 100 µl.
  Immunoprecipitation.
  Immunohistochemistry on frozen sections: use Aceton as fixative, Formaldehyde will destroy the epitope
  
• Reactivities: Chicken, Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Osteoclasts from osteoclastomas. Spleen cells from immunised mice were fused with cells of the mouse X63.Ag8.653 myeloma cell line.
• Specificity: This antibody recognises the intact complex formed between the CD51 and CD61 molecules (alpha V and beta 3 integrins). This complex binds vitronectin at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. 23C6 reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: integrin subunit alpha V
• Database Link:
  Entrez Gene 3685 Human
  UniProt ID P06756
• Synonyms: ITGB3, ITGB-3, GP3A, Platelet membrane glycoprotein IIIa, GPIIIa, CD61, Integrin beta-3, ITGAV, MSK8, VNRA, Vitronectin receptor subunit alpha, CD51, Integrin alpha-V, Vitronectin Receptor