Integrin alpha 4 (ITGA4) Mouse Monoclonal Antibody [Clone ID: 44H6]
Specifications
| Product Data | |
| Clone Name | 44H6 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | HOON pre-B leukaemia cell line |
| Specificity | This antibody recognizes CD49d. Clone 44H6 is reported to induce homoptic aggregation (see Ref.2). |
| Buffer | PBS, pH 7.2, with 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: FITC State: Liquid purified IgG fraction. Label: Fluorescein Isothiocyanate Isomer 1 |
| Concentration | lot specific |
| Purification | Protein G affinity Chromatography. |
| Conjugation | FITC |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | integrin subunit alpha 4 |
| Database Link | |
| Background | CD49d, also known as integrin alpha 4 subunit, associates with either integrin beta 1 (to form VLA-4) or beta 7. CD49d is expressed by lymphocytes, monocytes, eosinophils and thymocytes. VLA-4 mediates cell adhesion to VCAM-1 and fibronectin. |
| Synonyms | Integrin alpha-4, Integrin alpha-IV, VLA-4, VLA4 |
| Reference Data | |
| Protein Categories | CD Markers, Chemokines, Cytokines, Intracellular Proteins, Membrane Proteins |
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