CD11a (ITGAL) Mouse Monoclonal Antibody [Clone ID: 38]

CAT#: SM1080PS

CD11a (ITGAL) mouse monoclonal antibody, clone 38, Purified

Product Images

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD11

Specifications

Product Data

• Clone Name: 38
• Applications: FC, IHC, IP
• Recommended Dilution: Flow cytometry: Use 5 µl of 1/50-1/100 diluted antibody to label 10e6 cells in 100 µl.
  Immunoprecipitation.
  Immunohistochemistry on Frozen Sections.
  Recommended Positive Control: Human Tonsil.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Specificity: This antibody recognises the integrin alpha-L subunit, a 180kD glycoprotein expressed by all human leucocytes. The molecule is involved in cell-cell adhesion processes and binds to ICAM-1, 2 and 3.
• Formulation: State: Purified
  State: Liquid purified IgG fraction containing 0.09% Sodium Azide as preservative
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: integrin subunit alpha L
• Database Link:
  Entrez Gene 3683 Human
  UniProt ID P20701
• Background: CD11a is a member of the integrin family of cell adhesion molecules. It is a glycoprotein expressed in combination with the CD18 beta chain. The complex is a member of the beta 2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM2, ICAM3. CD11a is expressed on thymocytes, T and B lymphocytes, granulocytes, monocytes, and macrophages.
• Synonyms: Integrin alpha-L, LFA1, LFA-1