CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: 3G8]

CAT#: SM1072RX

CD16 (FCGR3A) mouse monoclonal antibody, clone 3G8, PE

Specifications

Product Data

• Clone Name: 3G8
• Recommended Dilution: Flow Cytometry: 1 μg is the maximum amount of reagent required for 1 x 10⁶ cells.
  Lesser amounts of antibody may be sufficient and it is recommended that the customer determines the optimum amount of antibody for each application.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody recognizes the CD16 antigen. This protein is a low affinity Fc receptor for immunoglobulin G. CD16 is expressed primarily on NK cells and neutrophils.
• Formulation: Label: PE
  State: Liquid IgG fraction
  Stabilizer: A highly purified grade of BSA has been added as a stabilizing protein to bring the final protein concentration to 4-5 mg/ml.
  Preservative: Sodium Azide
• Conjugation: PE
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
  
• Stability: Shelf life: one year from despatch.
• Gene Name: Fc fragment of IgG receptor IIIa
• Database Link:
  Entrez Gene 2214 Human
  UniProt ID P08637
• Background: CD16 (FcgammaRIII) serves as a low affinity IgG receptor. Human CD16 is expressed in two forms CD16a and CD16b. CD16a is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. CD16b is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
• Synonyms: FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2