Cd8a Rat Monoclonal Antibody [Clone ID: KT15]
Specifications
| Product Data | |
| Clone Name | KT15 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc recepto |
| Reactivity | Mouse |
| Antibody Host | Rat |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | T cell clone, C6. Spleen cells from a Spraque Dawley rat immunised with the C6 T cell clone were fused with cells of the NSO mouse myeloma cell line. |
| Specificity | Mouse Ly2.1 and Ly2.2 cells. This antibody reacts with the CD8 alpha chain (non polymorphic). |
| Buffer | PBS containing 0.09% Sodium Azide, 5% Sucrose and 1% Bovine Serum Albumin Label: APC State: Lyophilized purified IgG Label: Allophycocyanin |
| Reconstitution Method | Restore with 1 ml distilled water |
| Conjugation | APC |
| Storage | Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD8 antigen, alpha chain |
| Database Link | |
| Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. |
| Synonyms | CD8 alpha chain, CD8A, MAL |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins |
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in shipping.