Calcitonin (CALCA) Guinea Pig Polyclonal Antibody

CAT#: EUD6401

Calcitonin (CALCA) guinea pig polyclonal antibody, Serum

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Embedded or Frozen Tissue Sections.
  Immunofluorescence Microscopy: Dilute 1/800-1/1200 Using FITC with overnight incubation at 2-8°C.
  Recommended Positive Control: Frozen sections of Rat colon.
• Reactivities: Human, Mouse, Rat
• Host: Guinea Pig
• Clonality: Polyclonal
• Immunogen: Synthetic Calcitonin Gene Related Peptide (Peninsula), conjugated to BSA.
• Specificity: This antibody reacts with Calcitonin gene-related peptide (CGRP).
  Absoprtion with 10-100 µg CGRP per ml diluted antiserum abolishes the staining while Calcitonin does not.
  It does not cross-react with Amylin (IAPP).
• Formulation: State: Serum
  State: Lyophilized undiluted Serum
• Reconstitution Method: Restore in 100 µl distilled water.
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at 2-8°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: calcitonin related polypeptide alpha
• Database Link:
  Entrez Gene 796 Human
  UniProt ID P06881
• Background: The CGRP-sequence was predicted from the corresponding mRNA. CGRP is present in the C-cells of the thyroid and in nerves, in both brain and periphery, particularly within the sensory system. CGRP is a potent vasodilator, probably involved in neurogenic inflammation. Medullary carcinomas of the thyroid contain large amounts of CGRP.
• Synonyms: Calcitonin gene-related peptide I, Alpha-type CGRP, CALC1, CGRP-I