Gastrin (GAST) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1:50-1:100 in an ABC method (30 minutes at room temperature) Recommended Positive Control: Stomach |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Recombinant Gastrin conjugated to KLH. |
| Specificity | The antibody is specific against gastrin-containing cells. This antibody reacts with human gastrin I and human gastrin I fragments. Cellular Localization: Cytoplasmic |
| Buffer | containing sodium azide as preservative State: Purified State: Liquid serum |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | gastrin |
| Database Link | |
| Background | Gastrin is mainly known by its first described role as a gastric acid-hormone but the protein also has the ability to promote cellular growth. More recently, gastrin has been suggested to induce leukocyte-endothelial cell interactions and to have a pro-inflammatory effect. Gastrin has two biologically active peptide forms, G34 and G17 and they activate two different receptors: the CCK-1 receptor, which has low affinity for gastrin but high affinity for the related hormone cholecystokinin (CCK), and the CCK-2 receptor, which has high affinity for both gastrin and CCK and mediates the acid-secretory as well as the proliferative effects of gastrin. |
| Synonyms | GAST, GAS |
| Reference Data | |
| Protein Categories | Secreated Proteins |
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