Cytokeratin 5 (KRT5) Mouse Monoclonal Antibody [Clone ID: XM26]

CAT#: DM361

Cytokeratin 5 (KRT5) mouse monoclonal antibody, clone XM26, Supernatant

Specifications

Product Data

• Clone Name: XM26
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Embedded Sections: 1/50-1/75 (ABC method), Incubation of 30 minutes at room temperature.
  We suggest an Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
  Recommended Positive Control: Skin.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant protein corresponding to 103 amino acid portion of C-terminal region of the Human Cytokeratin 5 molecule
• Specificity: This antibody reacts with Cytokeratin 5 intermediate filament protein.
  Cellular Localization: Cytoplasmic.
• Formulation: State: Supernatant
  State: Liquid Culture Supernatant
  Preservative: < 0.1% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: keratin 5
• Database Link:
  Entrez Gene 3852 Human
  UniProt ID P13647
• Background: Basal cells of human epidermis express acidic Cytokeratin 14 and basic Cytokeratin 5. Cytokeratin 5 is a 58 kD protein, which is closely related to Cytokeratin 6. Cytokeratin 5 and 6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina, squamous cell carcinomas of skin, tongue, epiglottis and rectal-anal region.
  Cytokeratin 5 can be useful in the distinction of mesotheliomas from most adenocarcinomas.
• Synonyms: KRT5, Cytokeratin-5, Keratin-5, Keratin 5, CK5, K5