Pdpn Hamster Monoclonal Antibody [Clone ID: RTD4E10]

CAT#: DM3516P

Pdpn hamster monoclonal antibody, clone RTD4E10, Purified


USD 416.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name RTD4E10
Applications IHC, IP, WB
Recommended Dilution Immunohistochemistry on Frozen and Paraffin Sections: 1-10 µg/ml.
Western blot: 1-10 µg/ml. The antibody will detect a 36-40 kDa band.
Immunoprecipitation: 1-5 µg IgG per 1 ml lysate or reaction volume.
Reactivities Mouse
Host Hamster
Isotype IgG
Clonality Monoclonal
Immunogen Murine thymic stromal cell line
Specificity The monoclonal antibody will detect Podoplanin on the surface of lymphatic endothelial cells and some epithelial cell types by immunostaining or immunohistochemistry.
The antibody does not cross-react with Human Podoplanin.
Formulation PBS, pH 7.4, without preservatives or stabilizers
State: Purified
State: Lyophilized purified IgG fraction from Cell Culture Supernatant
Reconstitution Method Restore with sterile water to a concentration of 0.1-1.0 mg/ml.
Purification Protein G Chromatography
Conjugation Unconjugated
Storage

Prior to reconstitution store at 2-8°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Background Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a Mr 38,000 membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia.
Synonyms Glycoprotein 36, PA2.26 antigen, T1-alpha, Aggrus, PDPN, GP36, PSEC0003, PSEC0025
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.