HSP70-1A (HSPA1A) Mouse Monoclonal Antibody [Clone ID: W27]

CAT#: DM3097S

HSP70-1A (HSPA1A) mouse monoclonal antibody, clone W27, Supernatant

Product Images

Formalin fixed paraffin embedded human breast carcinoma stained with Heat shock protein 70 antibody. DM3097S

Specifications

Product Data

• Clone Name: W27
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on formalin-fixed paraffin embedded sections:
  diluted of 1:25-1:100 in an ABC method (30-60 minutes at room temperature)
  Recommended Positive Control: Breast carcinoma
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: BALB/C mice were injected with purified HSP70 protein.
• Specificity: This antibody is specific to constitutive (HSP73) and inducible (HSP72) form of HSP70.
  Cellular Localization: Cytoplasmic and nuclear
• Formulation: 10 mM citrate buffer, pH 6.0 - containing sodium azide as preservative.
  State: Supernatant
  State: Liquid Ig fraction
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: heat shock protein family A (Hsp70) member 1A
• Database Link:
  Entrez Gene 3303 Human
  UniProt ID P0DMV8
• Background: HSP70 is found to be associated with steroid receptors, actin, p53, polyoma T antigen, nucleotides and other known proteins. HSP70 has been shown to be involved in protective role against thermal stress, cytotoxic drugs and other damaging conditions.
• Synonyms: HSP70.1, HSP70-1/HSP70-2, HSPA1A, HSPA1B, HSPA1

Reference Data

• Protein Pathways: Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Prion diseases, Spliceosome