CD61 (ITGB3) Mouse Monoclonal Antibody [Clone ID: Y2/51]
$470.00
5 Days*
Specifications
| Product Data | |
| Clone Name | Y2/51 |
|---|---|
| Application | FC, IHC, WB |
| Recommended Dilution | Flow Cytometry: Use 10 µl of 1/100-1/200 diluted antibody to label 10e6 cells in 100 µl. Immunohistochemistry on Frozen and Paraffin Sections: This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin prior to staining. Western Blotting: Detects a band/s of approximately 90kDa in platelet lysates. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | PHA stimulated peripheral blood cells. Spleen cells from immunised Balb/c mice were fused with cells of the NS1 myeloma cell line. |
| Specificity | This antibody recognises CD61. |
| Buffer | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction. |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | integrin subunit beta 3 |
| Database Link | |
| Background | CD61 is a 105kD glycoprotein, which is also known as integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin. |
| Synonyms | Integrin beta-3, GP3A, GPIIIa |
| Reference Data | |
| Protein Categories | Allergies and autoimmune diseases, Cardiovascular diseases, CD Markers, Chemokines, Growth Factors, Intracellular Proteins, Membrane Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.