GCSF Receptor (CSF3R) Mouse Monoclonal Antibody [Clone ID: S-425]

CAT#: DM1057

GCSF Receptor (CSF3R) mouse monoclonal antibody, clone S-425, Purified

Specifications

Product Data

• Clone Name: S-425
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Immunoblotting: Recognizes denatured G-CSFR following SDS-PAGE and blotting of 200 ug of cell lysate or following immunoprecipitation with polyclonal antibody followed by immunoblotting.
  Western Blot: At an antibody concentration of 1-10 ug/mL will allow visualization of 250 ng/lane of human G-CSFR-MBP.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Purified recombinant MBP-GCSFR fusion protein
• Specificity: Reactive with G-CSFR and does not cross-react with MBP or BSA (bovine serum albumin).
• Formulation: 0.01M PBS, pH 7.2
  State: Purified
  State: Lyophilized purified IgG
• Reconstitution Method: Restore with double distillated water is recommended to adjust the final concentration to 1.00 mg/ml
• Purification: Protein G affinity purified
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: colony stimulating factor 3 receptor
• Database Link:
  Entrez Gene 1441 Human
  UniProt ID Q99062
• Background: The protein encoded by the GCSF Receptor gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, of which three are membrane-bound and the one secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.
• Synonyms: G-CSF-R, GCSFR, GCSF Receptor, G-CSF Receptor