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CD14 Mouse Monoclonal Antibody [Clone ID: MOP9.25]

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SKU
DDX0100P-100
CD14 mouse monoclonal antibody, clone MOP9.25
Size:
100 ug
Conjugation:
Unconjugated
  $645.00
2 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Clone Name MOP9.25
Application FC, IHC
Recommended Dilution Flow cytometry, cell depletion, IHC.
Usage recommendation:
*This monoclonal antibody may be used between 1-5 μg/ml for flow cytometry and 5-25 μg/ml for IHC
Reactivity Human
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen peripheral blood monocytes (patient with rheumatoid arthritis)
Specificity human CD14
Buffer State: Purified
State: 100 μg in 200 μl / 50 μg in 100 μl Tris-NaCl pH 8
Concentration lot specific
Purification QMA Hyper D ion exchange chromatography
Conjugation Unconjugated
Storage -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Shipping Blue Ice
Gene Name CD14 molecule
Database Link
Background CD14 recognizes a human monocyte/macrophage antigen of 55 kDa. It reacts with blood monocytes and has a weak reactivity on blood granulocytes, and interfollicular macrophages. Different cytokines have an effect on CD14 expression: CD14 expression was studied in dendritic cells generation in vitro. After 5 days in GMCSF + IL4, CD14 disappears while CD1a expression appears. TNF-α skews monocyte differentiation form macrophages to dendritic cells. The antibody MOP9.25 is used for monocyte depletion before dendritic cells sorting. (Dimitriu-Bona A., et al, J. Immunol., 1983 ; 130: 145-152 ; Banchereau J. et al, Annu. Rev. Immunol., 2000; 18: 767-811; Chomarat P. et al, J. Immunol., 2003; 171: 2262-2269).
Synonyms CD14
Reference Data
Protein Categories Allergies and autoimmune diseases, CD Markers, Cytokines, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.