PSMA (FOLH1) Mouse Monoclonal Antibody [Clone ID: OTI6B10]
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI6B10 |
|---|---|
| Application | IHC |
| Recommended Dilution | IHC 1:500 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human PSMA (NP_004467) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 84.2 kDa |
| Gene Name | folate hydrolase 1 |
| Database Link | |
| Background | This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. provided by RefSeq, Jul 2010 |
| Synonyms | FGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA |
| Reference Data | |
| Protein Categories | ADC Targets, CAR-T Targets, Enzyme: Peptidases, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Protease, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI6B10" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA814043 | PSMA mouse monoclonal antibody, clone OTI6B10 | 100 ul |
$447.00
|
|
| TA814043AM | PSMA mouse monoclonal antibody, clone OTI6B10, Biotinylated | 100 ul |
$509.00
|
|
| TA814043BM | PSMA mouse monoclonal antibody, clone OTI6B10, HRP conjugated | 100 ul |
$509.00
|
|
| TA814043S | PSMA mouse monoclonal antibody, clone OTI6B10 | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.