MYBPC3 Mouse Monoclonal Antibody [Clone ID: OTI1H1]

CAT#: CF813809

Carrier-free (BSA/glycerol-free) MYBPC3 mouse monoclonal antibody, clone OTI1H1

Formulation: Standard Carrier Free


  View other "OTI1H1" antibodies (2)

USD 600.00

4 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name
Applications ELISA
Recommended Dilution ELISA 1:5000-10000
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MYBPC3(C0-C1) (NP_000247) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Predicted Protein Size 140.8 kDa
Gene Name Homo sapiens myosin binding protein C3 (MYBPC3), mRNA.
Background MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
Synonyms CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C
Reference Data
Protein Families Druggable Genome
Protein Pathways Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.