CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: OTI12D8]
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI12D8 |
|---|---|
| Application | FC, WB |
| Recommended Dilution | WB 1:1000, FLOW 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human FCGR3A (NP_001121065) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 29.09 kDa |
| Gene Name | Fc fragment of IgG receptor IIIa |
| Database Link | |
| Background | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008. |
| Synonyms | CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20 |
| Reference Data | |
| Protein Categories | ADC Targets, Allergies and autoimmune diseases, CD Markers, Membrane Proteins, Secreated Proteins |
| Protein Families | ES Cell Differentiation/IPS, Secreted Protein, Transmembrane |
| Protein Pathways | Fc gamma R-mediated phagocytosis, Natural killer cell mediated cytotoxicity, Systemic lupus erythematosus |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI12D8" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA813633 | FCGR3A mouse monoclonal antibody, clone OTI12D8 | 100 ul |
$447.00
|
|
| TA813633AM | FCGR3A mouse monoclonal antibody, clone OTI12D8, Biotinylated | 100 ul |
$509.00
|
|
| TA813633BM | FCGR3A mouse monoclonal antibody, clone OTI12D8, HRP conjugated | 100 ul |
$509.00
|
|
| TA813633S | FCGR3A mouse monoclonal antibody, clone OTI12D8 | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.