Stefin B (CSTB) Mouse Monoclonal Antibody [Clone ID: OTI3D5]
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI3D5 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:500, IHC 1:500 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-98 of human CSTB (NP_000091) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 11 kDa |
| Gene Name | cystatin B |
| Database Link | |
| Background | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies. provided by RefSeq, Jul 2016 |
| Synonyms | CPI-B; CST6; EPM1; EPM1A; PME; STFB; ULD |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Nervous system Diseases |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3D5" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA813049 | CSTB mouse monoclonal antibody,clone OTI3D5 | 100 ul |
$447.00
|
|
| TA813049AM | CSTB mouse monoclonal antibody,clone OTI3D5, Biotinylated | 100 ul |
$509.00
|
|
| TA813049BM | CSTB mouse monoclonal antibody,clone OTI3D5, HRP conjugated | 100 ul |
$509.00
|
|
| TA813049S | CSTB mouse monoclonal antibody,clone OTI3D5 | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.