RACGAP1 Mouse Monoclonal Antibody [Clone ID: OTI3A5]

CAT#: CF811639

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Carrier-free (BSA/glycerol-free) RACGAP1 mouse monoclonal antibody,clone OTI3A5



  View other "OTI3A5" antibodies (4)

USD 600.00


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Size
    • 100 ug


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Specifications

Product Data
Clone Name OTI3A5
Applications IHC, WB
Recommended Dilution WB 1:500~2000, IHC 1:2000
Reactivities Human, Monkey, Mouse, Rat
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 123-238 of human RACGAP1 (NP_001119575) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name Homo sapiens Rac GTPase activating protein 1 (RACGAP1), transcript variant 2, mRNA.
Background This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016]
Synonyms CYK4; HsCYK-4; ID-GAP; MgcRacGAP
Reference Data
Protein Families Druggable Genome

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