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Androgen Receptor (AR) Mouse Monoclonal Antibody [Clone ID: OTI2E11]

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SKU
CF809203
Carrier-free (BSA/glycerol-free) AR mouse monoclonal antibody, clone OTI2E11
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "Androgen Receptor or NM_000044" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2E11
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:1000
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 420-659 of human AR(NP_000035) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 99 kDa
Gene Name androgen receptor
Database Link
Background The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. provided by RefSeq, Jul 2008
Synonyms AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM
Reference Data
Protein Categories Growth Factors, Intracellular Proteins, Nervous system: Neurodegenerative diseases, Transciption Factors
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Oocyte meiosis, Pathways in cancer, Prostate cancer
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Resources
Other "OTI2E11" antibodies (4)
SKU Description Size Price
TA809203 AR mouse monoclonal antibody,clone OTI2E11 100 ul
$447.00
TA809203AM AR mouse monoclonal antibody,clone OTI2E11, Biotinylated 100 ul
$509.00
TA809203BM AR mouse monoclonal antibody,clone OTI2E11, HRP conjugated 100 ul
$509.00
TA809203S AR mouse monoclonal antibody,clone OTI2E11 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.