NOB1 Mouse Monoclonal Antibody [Clone ID: OTI4H3]
SKU
CF808806
Carrier-free (BSA/glycerol-free) NOB1 mouse monoclonal antibody, clone OTI4H3 (formerly 4H3)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI4H3 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 2-234 of human NOB1(NP_054781) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 46.5 kDa |
| Gene Name | NIN1 (RPN12) binding protein 1 homolog |
| Database Link | |
| Background | In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 PubMed 19706509). supplied by OMIM, Nov 2010. Transcript Variant: This variant (2) lacks an internal exon, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG386829.1 ECO:0000332 RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 ECO:0000350 ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
| Synonyms | ART-4; MST158; MSTP158; NOB1P; PSMD8BP1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4H3" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA808806 | NOB1 mouse monoclonal antibody, clone OTI4H3 (formerly 4H3) | 100 ul |
$447.00
|
|
| TA808806AM | NOB1 mouse monoclonal antibody, clone OTI4H3 (formerly 4H3), Biotinylated | 100 ul |
$509.00
|
|
| TA808806BM | NOB1 mouse monoclonal antibody, clone OTI4H3 (formerly 4H3), HRP conjugated | 100 ul |
$509.00
|
|
| TA808806S | NOB1 mouse monoclonal antibody, clone OTI4H3 (formerly 4H3) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.